Copper Tripeptide-1 · Gly-His-Lys
Copper peptide complex. Studied in collagen synthesis and matrix remodeling.
GHK-Cu (copper tripeptide-1) is a naturally occurring plasma peptide that declines with age. Research by Pickart and others has demonstrated it stimulates collagen, glycosaminoglycan, and decorin synthesis, activates antioxidant enzymes, and modulates the expression of over 4,000 human genes involved in skin repair, anti-inflammatory signaling, and cellular remodeling.
Store lyophilized at -20°C. Reconstituted in BAC water: 2–8°C, use within 4–6 weeks.
GHK-Cu is a naturally occurring tripeptide (glycyl-histidyl-lysine) bound to a copper(II) ion. It circulates in human plasma at around 200 ng/mL at age 20, falling to about 80 ng/mL by age 60, the observation that framed Pickart's foundational research.
A 2010 Broad Institute Connectivity Map analysis found GHK modulates the expression of more than 4,000 human genes. The most studied effects are on skin and connective tissue: increased collagen, fibronectin and glycosaminoglycan synthesis in fibroblast models, and balanced matrix turnover.
For the full study list, published safety data and links to each paper, see the GHK-Cu research page.
The 50 mg size ships from US stock, usually arriving in 2-5 days by UPS with tracking. The 100 mg size made to order and usually ships in about a week. International orders are kits only and usually arrive 7-14 days after dispatch.
$40 per order for kits in the US ($20 when the order is single vials only), $60 for kits shipped internationally, and free on US orders of $1,000 or more.
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Every size is the same compound and purity; the size only changes how much material is in each vial, and larger sizes cost less per milligram. If you are unsure, message us on Telegram and we will help.